Mechanisms of transcription initiation

Transcription start site (TSS) selection has downstream regulatory consequences on the expression of a gene. I am interested in using data across different kinds of sequencing assays to investigate the kinetics around TSS selection and how a cell can drive initiation at certain TSSs over others.

Keywords

Genome Regulation Transcription initiation ChIP-exo RNA-seq PRO-cap

ScriptManager

ScriptManager is a generalized collection of scripts for analyzing genomic datasets (perfect for non-bioinformaticians) for a broad variety of biochemical sequencing assays.

Keywords

Tool development NGS sequencing Data analysis Build workflows Reproducibility

Software & Documentation

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GenoPipe

GenoPipe is a quality control tool for analyzing NGS datasets for three different types of genetic backgrounds for a quick post-sequencing check that the strain background of the sample matches the expectation.

Keywords

Tool development Quality control NGS sequencing Reproducibility

Software & Documentation

View on GitHub